2025
Automation of 99mTc mercaptoacetyltriglycine (MAG3) report writing using a vision language model Wolfram Andreas Bosbach 1, Christoph L Clement 2, Franziska Strunz 2, Foroud Aghapour Zangeneh 2, Nasir Gözlügöl 2, Carola Maria Bregenzer 2, Clemens Mingels 2, Pia Koller 2, Konstantinos Zeimpekis 2, Kuangyu Shi 2, Axel Rominger 2, Robert Seifert 3 Affiliations Expand PMID: 41324797 PMCID: PMC12686326 DOI: 10.1186/s13550-025-01323-6
Diagnostic Accuracy of Fourth Universal Definition ECG Criteria for Identifying Prior Myocardial Infarction Martin Segeroth 1, Patrick Badertscher 2, Ivo Strebel 2, Jan Gerrit van der Stouwe 2, Jude Formambuh 2, Federico Caobelli 3, Antonio Madaffari 4, Gregor Sommer 5, Pedro Lopez-Ayala 2, Simon M Frey 2, Michael Kuehne 2, Christian Sticherling 2, Maurice Pradella 1, Michael J Zellweger 2, Christian Mueller 2, Jens Bremerich 1, Philip Haaf 2 Affiliations Expand PMID: 41410574 DOI: 10.1148/ryct.250082
Diagnostic Accuracy of Fourth Universal Definition ECG Criteria for Identifying Prior Myocardial Infarction Martin Segeroth 1, Patrick Badertscher 2, Ivo Strebel 2, Jan Gerrit van der Stouwe 2, Jude Formambuh 2, Federico Caobelli 3, Antonio Madaffari 4, Gregor Sommer 5, Pedro Lopez-Ayala 2, Simon M Frey 2, Michael Kuehne 2, Christian Sticherling 2, Maurice Pradella 1, Michael J Zellweger 2, Christian Mueller 2, Jens Bremerich 1, Philip Haaf 2 Affiliations Expand PMID: 41410574 DOI: 10.1148/ryct.250082
Efficacy and safety of rechallenge therapy with [177Lu]Lu-PSMA in metastatic castration-resistant prostate cancer: a systematic review and meta-analysis Zineddine Belabaci 1, Leonie Schmidt 2, Mouhammed Sleiay 3, Felipe Couñago 4, Fernando López Campos 5, Marwan Tolba 6, Thomas Zilli 7 8 9, Ali Afshar-Oromieh 10, Mohamed Shelan 11 Affiliations Expand PMID: 40705094 PMCID: PMC12660338 DOI: 10.1007/s00259-025-07438-1
Intermittent hydrarthrosis of both knees successfully treated with radiosynoviorthesis using 90Y-Citrat Ali Afshar-Oromieh 1, Nasir Gözlügöl 1, Theresa Schreder 2, Stefan Kuchen 3, Axel Rominger 1, Keivan Daneshvar 4 Affiliations Expand PMID: 41297548 DOI: 10.1055/a-2710-7068 No abstract available PubMed Disclaimer
Neuro-symbolic AI for auditable cognitive information extraction from medical reports George A Prenosil # 1 2, Thilo K Weitzel # 3, Sandra C Bello 4, Clemens Mingels 5, Giulia Manzini 5, Lorenz P Meier 5, Kuang-Yu Shi 5, Axel Rominger 5, Ali Afshar-Oromieh 5 Affiliations Expand PMID: 41272253 PMCID: PMC12638795 DOI: 10.1038/s43856-025-01194-x
Visual grading for noninvasive assessment of transthyretin-related cardiomyopathy with bone scintigraphy: time for moving forward? Federico Caobelli 1, Sharmila Dorbala 2 Affiliations Expand PMID: 40553117 DOI: 10.1007/s00259-025-07410-z No abstract available PubMed Disclaimer
Advances in Dosimetry and Imaging for 203Pb and 212Pb Radiotheranostics Keamogetswe Ramonaheng 1, Milani Qebetu 2, Kaluzi Banda 2, Pryaska Goorhoo 2, Khomotso Legodi 3, Sipho Mdanda 2, Sandile Sibiya 2, Yonwaba Mzizi 2, Honest Ndlovu 2, Joseph Kabunda 2, Mengdie Yang 4, Kuangyu Shi 5, Mike Sathekge 2 Affiliations Expand PMID: 41062349 DOI: 10.1053/j.semnuclmed.2025.09.006 Free article
Erratum in Corrigendum to <Advances in Dosimetry and Imaging for 203Pb and 212Pb Radiotheranostics'> <[Semin NuclMed55:1011-1031/https://doi.org/10.1053/j.semnuclmed.2025.09.006]> Ramonaheng K, Qebetu M, Banda K, Goorhoo P, Legodi K, Mdanda S, Sibiya S, Mzizi Y, Ndlovu H, Kabunda J, Yang M, Shi K, Sathekge M.Semin Nucl Med. 2026 May;56(3):564-565. doi: 10.1053/j.semnuclmed.2026.02.003. Epub 2026 Mar 6.PMID: 41791913 No abstract available.
Advancing Positron Emission Tomography Image Quantification: Artificial Intelligence-Driven Methods, Clinical Challenges, and Emerging Opportunities in Long-Axial Field-of-View Positron Emission Tomography/Computed Tomography Imaging Fereshteh Yousefirizi 1, Movindu Dassanayake 2, Alejandro Lopez 3, Andrew Reader 4, Gary J R Cook 5, Clemens Mingels 3, Arman Rahmim 6, Robert Seifert 3, Ian Alberts 7 Affiliations Expand PMID: 40885661 DOI: 10.1016/j.cpet.2025.07.010
Artificial Intelligence-Guided PET Image Reconstruction and Multi-Tracer Imaging: Novel Methods, Challenges, and Opportunities Movindu Dassanayake 1, Alejandro Lopez 2, Andrew Reader 3, Gary J R Cook 4, Clemens Mingels 2, Arman Rahmim 5, Robert Seifert 2, Ian Alberts 6, Fereshteh Yousefirizi 7 Affiliations Expand PMID: 40858423 DOI: 10.1016/j.cpet.2025.07.005
Noninvasive Anatomical and Functional Imaging for Hemodynamic Relevance in Right Coronary Artery Anomalies Marius R Bigler 1, Anselm W Stark 1, Federico Caobelli 2, Axel Rominger 2, Ryota Kakizaki 1, Flavio G Biccirè 1, Saddam M A Al-Sabri 1, Isaac Shiri 1, Matthias Siepe 3, Stephan Windecker 1 4, Lorenz Räber 1, Christoph Gräni 1 Affiliations Expand PMID: 40928770 PMCID: PMC12423952 DOI: 10.1001/jamacardio.2025.2993
The sense and nonsense of antipsychotic combinations: A model for dopamine D2/3 receptor occupancy Moritz Spangemacher 1 2 3, Christian N Schmitz 1 2 3, Paul Cumming 4 5, Luca V Färber 1 3, Xenia M Hart 1 6, Hiroyuki Uchida 6, Gerhard Gründer 7 8 Affiliations Expand PMID: 41034210 PMCID: PMC12488982 DOI: 10.1038/s41398-025-03582-2
Synthesis and In Silico Profile Modeling of 6- O-Fluoroalkyl-6- O-desmethyl-diprenorphine Analogs János Marton 1, Dávid Gombos 2 3, Paul Cumming 4 5, Tamás Fehér 2 6, Alexander Milentyev 1, Beate Bauer 1, Frode Willoch 7, Bent Wilhelm Schoultz 8 9, Sándor Benyhe 2, Ferenc Ötvös 2 Affiliations Expand PMID: 41096695 PMCID: PMC12524955 DOI: 10.3390/ijms26199427
Correction: Phantom imaging demonstration of positronium lifetime with a long axial field‑of‑view PET/CT and 124I Lorenzo Mercolli 1 2 3, William M Steinberger 4, Narendra Rathod 5 6, Maurizio Conti 4, Paweł Moskal 7 8, Axel Rominger 5, Robert Seifert 5, Kuangyu Shi 5, Ewa Ł Stępień 7 8, Hasan Sari 5 6 9 Affiliations Expand PMID: 40960667 PMCID: PMC12443642 DOI: 10.1186/s40658-025-00801-z
Response to letter to the editor regarding “Contemporaneous Outcomes Multiple Imputation (KOMI) Can Communicate Missing Glasgow Outcome Scale - Extended (GOSE) scores: A multi-domain imputation for GOSE In the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) data” Xuan Vinh To 1, Hien D Nguyen 2, Paul Cumming 3, Fatima A Nasrallah 4 Affiliations Expand PMID: 40752346 DOI: 10.1016/j.jns.2025.123645
Lymphoma Therapy Response Assessment with Low-Dose [18F]FDG Total-Body PET/CT Clemens Mingels 1 2, Kevin J Chung 3, Hande Nalbant 3, Yasser G Abdelhafez 3, Naseem S Esteghamat 4, Mehrad Rokni 3, Shervin Zoghi 3, Joseph M Tuscano 4 5, Axel Rominger 2, Ramsey D Badawi 3, Benjamin A Spencer 3, Lorenzo Nardo 3 Affiliations Expand PMID: 40813234 PMCID: PMC12410293 DOI: 10.2967/jnumed.124.268841
Annual percentage change of MR Parkinsonism index in progressive supranuclear palsy: a feasibility study Min Wang # 1, Jiaying Lu # 2, Ling Li # 3, Fengtao Liu 4, Fangyang Jiao 2, Ping Wu 2, Jingjie Ge 2, Luyao Wang 1, Matthias Brendel 5, Axel Rominger 6, Kuangyu Shi 6 7, Jian Wang 4, Chuantao Zuo 8 9, Jiehui Jiang 10; Progressive Supranuclear Palsy Neuroimage Initiative (PSPNI) Collaborators, Affiliations Expand PMID: 40000508 DOI: 10.1007/s00330-025-11440-4
A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers Martina DI Franco 1, Andrea DI Giorgio 1, Andrea Farolfi 2, Michelle Amon 3, Clemens Mingels 3, Lorenzo Nardo 4, Elizabeth K Triumbari 5 6 Affiliations Expand PMID: 41030167 PMCID: PMC12856956 DOI: 10.23736/S1824-4785.25.03656-8
FAPI PET Versus FDG PET/CT in Gastrointestinal Cancers: An Overview Zhaoguo Lin 1, Pawel Rasinski 2, Ted Nilsson 2, Maria Holstensson 2, Yangmeihui Song 3, August Blomgren 4, Warissara Jutidamrongphan 4, Kalyani Pandya 4, Jimin Hong 4, Axel Rominger 4, Kuangyu Shi 4, Rimma Axelsson 5, Xiaoli Lan 3, Robert Seifert 6 Affiliations Expand PMID: 40399164 DOI: 10.1053/j.semnuclmed.2025.04.006
New Promising Targets for Imaging in Cardiovascular Diseases Mia Ståhle 1, Cristina Popescu 2, Christoph Rischpler 3, Han Zhang 4, Samia Massalha 5, Leonor Lopes 6, Axel Rominger 6, Federico Caobelli 7 Affiliations Expand PMID: 40555628 DOI: 10.1053/j.semnuclmed.2025.05.006
Evaluating 18F-Florzolotau tau PET for Alzheimer's disease diagnosis with 18F-Flortaucipir as reference Qi Zhang # 1, Jiaying Lu # 2, Luyao Wang 3, Fangyang Jiao 2, Min Wang 3, Kuangyu Shi 4, Chuantao Zuo 5, Jiehui Jiang 6; Alzheimer’s Disease Neuroimaging Initiative Affiliations Expand PMID: 40877423 DOI: 10.1007/s00415-025-13342-3EJNMMI Phys
Phantom imaging demonstration of positronium lifetime with a long axial field-of-view PET/CT and 124I Lorenzo Mercolli 1 2 3, William M Steinberger 4, Narendra Rathod 5 6, Maurizio Conti 4, Paweł Moskal 7 8, Axel Rominger 5, Robert Seifert 5, Kuangyu Shi 5, Ewa Ł Stępień 7 8, Hasan Sari 5 6 9 Affiliations Expand PMID: 40855031 PMCID: PMC12379202 DOI: 10.1186/s40658-025-00790-z
Contemporaneous Outcomes Multiple Imputation (KOMI) can communicate missing Glasgow Outcome Scale - Extended (GOSE) scores: A multi-domain imputation for GOSE in the transforming research and clinical knowledge in traumatic brain injury (TRACK-TBI) data Xuan Vinh To 1, Hien D Nguyen 2, Paul Cumming 3, Peter Curpen 1, Fatima A Nasrallah 4 Affiliations Expand PMID: 40505353 DOI: 10.1016/j.jns.2025.123564
Anomaly Detection in Medical Images Using Encoder-Attention-2Decoders Reconstruction Peng Tang, Xiaoxiao Yan, Xiaobin Hu, Kai Wu, Tobias Lasser, Kuangyu Shi PMID: 40293916 DOI: 10.1109/TMI.2025.3563482
Population pharmacokinetic-pharmacodynamic modeling of co-administered N,N-dimethyltryptamine and harmine in healthy subjects Angela Äbelö 1, John W Smallridge 2, Robin von Rotz 3, Dario A Dornbierer 3, Klemens Egger 4, Michael Ashton 1, Milan Scheidegger 3 Affiliations Expand PMID: 40639043 DOI: 10.1016/j.biopha.2025.118329
Prognostic value of [18F]fluorodeoxyglucose-PET/MRI(CT) novel interpretation criteria (IMPeTUs) in multiple myeloma Miao Zhang # 1, Tangjia Cai # 1, Shiwei Jin # 2, Xinyun Huang # 1, Yuting Gao 1, Xiaoyue Chen 1, Wanyan Ouyang 2, Yi Tao 2, Yuanfang Liu 2, Yan Wang 2, Hongping Meng 1, Jian Li 3, Xiaozhu Lin 1, Kuangyu Shi 4, Jin Wang 2, Xiaoyi Ding 5, Jian-Qing Mi 6, Biao Li 7 8 Affiliations Expand PMID: 40175849 DOI: 10.1007/s00259-025-07219-w
Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain Korbinian Krieger 1 2, Thomas Pyka 1, Clemens Mingels 1, Hasan Sari 1, Albert Gjedde 3 4 5, Axel Rominger 1, Paul Cumming 6 7 Affiliations Expand PMID: 40694259 PMCID: PMC12283531 DOI: 10.1186/s13550-025-01279-7
A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers Martina DI Franco 1, Andrea DI Giorgio 1, Andrea Farolfi 2, Michelle Amon 3, Clemens Mingels 3, Lorenzo Nardo 4, Elizabeth K Triumbari 5 6 Affiliations Expand PMID: 41030167 PMCID: PMC12856956 DOI: 10.23736/S1824-4785.25.03656-8
FAPI PET Versus FDG PET/CT in Gastrointestinal Cancers: An Overview Zhaoguo Lin 1, Pawel Rasinski 2, Ted Nilsson 2, Maria Holstensson 2, Yangmeihui Song 3, August Blomgren 4, Warissara Jutidamrongphan 4, Kalyani Pandya 4, Jimin Hong 4, Axel Rominger 4, Kuangyu Shi 4, Rimma Axelsson 5, Xiaoli Lan 3, Robert Seifert 6 Affiliations Expand PMID: 40399164 DOI: 10.1053/j.semnuclmed.2025.04.006
New Promising Targets for Imaging in Cardiovascular Diseases Mia Ståhle 1, Cristina Popescu 2, Christoph Rischpler 3, Han Zhang 4, Samia Massalha 5, Leonor Lopes 6, Axel Rominger 6, Federico Caobelli 7 Affiliations Expand PMID: 40555628 DOI: 10.1053/j.semnuclmed.2025.05.006
Evaluating 18F-Florzolotau tau PET for Alzheimer's disease diagnosis with 18F-Flortaucipir as reference Qi Zhang # 1, Jiaying Lu # 2, Luyao Wang 3, Fangyang Jiao 2, Min Wang 3, Kuangyu Shi 4, Chuantao Zuo 5, Jiehui Jiang 6; Alzheimer’s Disease Neuroimaging Initiative Affiliations Expand PMID: 40877423 DOI: 10.1007/s00415-025-13342-3
Phantom imaging demonstration of positronium lifetime with a long axial field-of-view PET/CT and 124I Lorenzo Mercolli 1 2 3, William M Steinberger 4, Narendra Rathod 5 6, Maurizio Conti 4, Paweł Moskal 7 8, Axel Rominger 5, Robert Seifert 5, Kuangyu Shi 5, Ewa Ł Stępień 7 8, Hasan Sari 5 6 9 Affiliations Expand PMID: 40855031 PMCID: PMC12379202 DOI: 10.1186/s40658-025-00790-z
Erratum in Correction: Phantom imaging demonstration of positronium lifetime with a long axial field‑of‑view PET/CT and 124I. Mercolli L, Steinberger WM, Rathod N, Conti M, Moskal P, Rominger A, Seifert R, Shi K, Stępień EŁ, Sari H.EJNMMI Phys. 2025 Sep 17;12(1):83. doi: 10.1186/s40658-025-00801-z.PMID: 40960667 Free PMC article. No abstract available.
Contemporaneous Outcomes Multiple Imputation (KOMI) can communicate missing Glasgow Outcome Scale - Extended (GOSE) scores: A multi-domain imputation for GOSE in the transforming research and clinical knowledge in traumatic brain injury (TRACK-TBI) data Xuan Vinh To 1, Hien D Nguyen 2, Paul Cumming 3, Peter Curpen 1, Fatima A Nasrallah 4 Affiliations Expand PMID: 40505353 DOI: 10.1016/j.jns.2025.123564
Anomaly Detection in Medical Images Using Encoder-Attention-2Decoders Reconstruction Peng Tang, Xiaoxiao Yan, Xiaobin Hu, Kai Wu, Tobias Lasser, Kuangyu Shi PMID: 40293916 DOI: 10.1109/TMI.2025.3563482
Population pharmacokinetic-pharmacodynamic modeling of co-administered N,N-dimethyltryptamine and harmine in healthy subjects Angela Äbelö 1, John W Smallridge 2, Robin von Rotz 3, Dario A Dornbierer 3, Klemens Egger 4, Michael Ashton 1, Milan Scheidegger 3 Affiliations Expand PMID: 40639043 DOI: 10.1016/j.biopha.2025.118329
Prognostic value of [18F]fluorodeoxyglucose-PET/MRI(CT) novel interpretation criteria (IMPeTUs) in multiple myeloma Miao Zhang # 1, Tangjia Cai # 1, Shiwei Jin # 2, Xinyun Huang # 1, Yuting Gao 1, Xiaoyue Chen 1, Wanyan Ouyang 2, Yi Tao 2, Yuanfang Liu 2, Yan Wang 2, Hongping Meng 1, Jian Li 3, Xiaozhu Lin 1, Kuangyu Shi 4, Jin Wang 2, Xiaoyi Ding 5, Jian-Qing Mi 6, Biao Li 7 8 Affiliations Expand PMID: 40175849 DOI: 10.1007/s00259-025-07219-w
Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain Korbinian Krieger 1 2, Thomas Pyka 1, Clemens Mingels 1, Hasan Sari 1, Albert Gjedde 3 4 5, Axel Rominger 1, Paul Cumming 6 7 Affiliations Expand PMID: 40694259 PMCID: PMC12283531 DOI: 10.1186/s13550-025-01279-7
Multimodal Imaging Evaluation of Myocardial Involvement in Rare Oculoleptomeningeal Hereditary Transthyretin Amyloidosis Moritz J Hundertmark 1, Martin Zinkernagel 2, Tatiana Brémova-Ertl 3, Pascal Escher 2, Anina Bauer 4, Federico Caobelli 5, Yara Banz 6, Andreas Flammer 7, Michele V Martinelli 8, Christoph Gräni 9 Affiliations Expand PMID: 40681261 PMCID: PMC12441426 DOI: 10.1016/j.jaccas.2025.104034
Synaptic loss pattern is constrained by brain connectome and modulated by phosphorylated tau in Alzheimer's disease Ying Luan # 1 2, Weiyi Wang # 1, Qi Huang # 1, Yan Wang 1, Jana Nussbaumer 3, Jie Wang 1, Anna Steward 4, Sebastian N Roemer-Cassiano 4 5 6, Yihui Guan 1, Michael Ewers 4, Michael Schöll 7 8 9 10, Ruiqing Ni 11 12, Binyin Li 13, Nicolai Franzmeier 4 8 14, Fang Xie 15 16 Affiliations Expand PMID: 40640137 PMCID: PMC12246497 DOI: 10.1038/s41467-025-61497-4
Model selection for dynamic PET compartmental modelling of 18F-FDG uptake using a long axial field-of-view PET scanner with delay and motion correction Hamed Moradi 1 2 3, Rajat Vashistha 1 2, Kieran O'Brien 1 2 3, Amanda Hammond 2 3, Axel Rominger 4, Hasan Sari 4 5, Kuangyu Shi 4, Viktor Vegh 6 7, David Reutens 1 2 Affiliations Expand PMID: 40613830 PMCID: PMC12227408 DOI: 10.1186/s13550-025-01277-9
A mathematical model for the investigation of combined treatment of radiopharmaceutical therapy and PARP inhibitors Marc Ryhiner 1, Yangmeihui Song 2 3, Jimin Hong 4, Carlos Vinícius Gomes Ferreira 4, Axel Rominger 4, Susanne Kossatz 2, Gerhard Glatting 5, Wolfgang Weber 2, Kuangyu Shi 4 Affiliations Expand PMID: 40000461 PMCID: PMC12222425 DOI: 10.1007/s00259-025-07144-y
Data-efficient generalization of AI transformers for noise reduction in ultra-fast lung PET scans Jiale Wang 1, Xinyu Zhang 2 3, Ying Miao 2 3, Song Xue 4, Yu Zhang 2 3, Kuangyu Shi 4 5, Rui Guo 2 3, Biao Li 6 7, Guoyan Zheng 8 Affiliations Expand PMID: 40009163 DOI: 10.1007/s00259-025-07165-7
Diagnostic accuracy in NSCLC lymph node staging with Total-Body and conventional PET/CT Clemens Mingels 1 2, Mohammad H Madani 3, Fatma Sen 3, Hande Nalbant 3, Jonathan W Riess 4, Yasser G Abdelhafez 3 5, Ahmadreza Ghasemiesfe 3, Axel Rominger 6, Michele Guindani 7, Ramsey D Badawi 3 8, Benjamin A Spencer 3, Lorenzo Nardo 3 Affiliations Expand PMID: 40113643 PMCID: PMC12222388 DOI: 10.1007/s00259-025-07177-3
Improved FAPI-radiopharmaceutical pharmacokinetics from the perspectives of a dose escalation study Adrianna Bilinska 1, Sanjana Ballal 2, Chandrasekhar Bal 2, Tilman Läppchen 1, Eirinaios Pilatis 1, Elena Menéndez 1, Euy Sung Moon 3, Marcel Martin 3, Frank Rösch 3, Axel Rominger 1, Eleni Gourni 4 Affiliations Expand PMID: 40000459 PMCID: PMC12222399 DOI: 10.1007/s00259-025-07141-
New semiquantitative parameters in digital [18F]FDG PET/CT improve diagnostic accuracy in suspected infective endocarditis Carola Maria Bregenzer 1, Luisa Maria Knappe 1, Alexander Weissensee 1, Nasir Gözlügöl 1, Ali Afshar-Oromieh 1, Clemens Mingels 1, Christoph Gräni 2, Axel Rominger 1, Federico Caobelli 3 Affiliations Expand PMID: 40545521 PMCID: PMC12183137 DOI: 10.1186/s41824-025-00256-6
Medulla oblongata dominated synaptic density network degeneration in amyotrophic lateral sclerosis Ting Zou 1, Manliu Hou 2, Honghao Han 1, Xuyang Wang 1, Huafu Chen 3, Yongxiang Tang 4, Rong Li 5, Shuo Hu 6 Affiliations Expand PMID: 40543321 PMCID: PMC12216726 DOI: 10.1016/j.nicl.2025.103814
Feasibility of an Ultra-Low-Dose PET Scan Protocol with CT-Based and LSO-TX-Based Attenuation Correction Using a Long-Axial-Field-of-View PET/CT Scanner Hasan Sari 1 2, Mohammadreza Teimoorisichani 3, Marco Viscione 4, Clemens Mingels 4 5, Robert Seifert 4, Kuangyu Shi 4, Michael Morris 6, Eliot Siegel 6, Babak Saboury 6, Thomas Pyka 4, Axel Rominger 4 Affiliations Expand PMID: 40210420 DOI: 10.2967/jnumed.124.268380
Is Long-Axial-Field-of-View PET/CT Cost-Effective? An International Health-Economic Analysis Ian Alberts 1 2, Stuart More 3, Karen Knapp 4, Riccardo Mei 5, Stefano Fanti 5, Clemens Mingels 6 7, Lorenzo Nardo 7, Nii Boye Hammond 8, Harish Nagaraj 9, Axel Rominger 6, Gary J R Cook 10, Don Wilson 11 2 Affiliations Expand PMID: 40246541 DOI: 10.2967/jnumed.124.269203
Artificial intelligence-based cardiac transthyretin amyloidosis detection and scoring in scintigraphy imaging: multi-tracer, multi-scanner, and multi-center development and evaluation study Yazdan Salimi 1, Isaac Shiri 2, Zahra Mansouri 1, Amirhossein Sanaat 1, Ghasem Hajianfar 1, Elsa Hervier 1, Ahmad Bitarafan 3, Federico Caobelli 4, Moritz Hundertmark 2, Ismini Mainta 1, Christoph Gräni 2, René Nkoulou 1, Habib Zaidi 5 6 7 8 Affiliations Expand PMID: 39907796 PMCID: PMC12119773 DOI: 10.1007/s00259-025-07117-1
Med Phys. 2025 Jun;52(6):3970-3980. doi: 10.1002/mp.17684. Epub 2025 Feb 11. Automatic bone marrow segmentation for precise [177Lu]Lu-PSMA-617 dosimetry Zhonglin Lu 1 2, Jiaxi Hu 3, Gefei Chen 1, Han Jiang 1 4, Cheng-Ting Shih 5, Ali Afshar-Oromieh 3, Axel Rominger 3, Kuangyu Shi 3, Greta S P Mok 1 2 6 Affiliations Expand PMID: 39935268 PMCID: PMC12149722 DOI: 10.1002/mp.17684
Evaluation of deep learning-based scatter correction on a long-axial field-of-view PET scanner Baptiste Laurent 1, Alexandre Bousse 2, Thibaut Merlin 1, Axel Rominger 3, Kuangyu Shi 3, Dimitris Visvikis 1 Affiliations Expand PMID: 39918764 DOI: 10.1007/s00259-025-07120-6
Robust whole-body PET image denoising using 3D diffusion models: evaluation across various scanners, tracers, and dose levels Boxiao Yu 1, Savas Ozdemir 2, Yafei Dong 3, Wei Shao 4, Tinsu Pan 5, Kuangyu Shi 6, Kuang Gong 7 Affiliations Expand PMID: 39912940 PMCID: PMC12119227 DOI: 10.1007/s00259-025-07122-4
The Added Value of Prostate-specific Membrane Antigen Positron Emission Tomography/Computed Tomography to Magnetic Resonance Imaging for Local Staging of Prostate Cancer in Patients Undergoing Radical Prostatectomy Timo F W Soeterik 1, Joris G Heetman 2, Rick Hermsen 3, Lieke Wever 2, Jules Lavalaye 4, Maarten Vinken 3, Clinton D Bahler 5, Courtney Yong 5, Mark Tann 6, Claudia Kesch 7, Robert Seifert 8, Tugce Telli 9, Peter Ka-Fung Chiu 10, Kwan Kit Wu 11, Fabio Zattoni 12, Laura Evangelista 13, Sara Bettella 14, Francesco Ceci 15, Antonio Barone 15, Marcin Miszczyk 16, Akihiro Matsukawa 17, Pawel Rajwa 18, Giancarlo Marra 19, Alberto Briganti 20, Francesco Montorsi 20, Matthijs J Scheltema 2, Jean-Paul A van Basten 21, Harm H E van Melick 2, Roderick C N van den Bergh 22, Giorgio Gandaglia 20; European Association of Urology Young Academic Urologists Prostate Cancer Working Party Affiliations Expand PMID: 39613565 DOI: 10.1016/j.euo.2024.11.002
Prediction of longitudinal synaptic loss in Alzheimer's disease using tau PET and plasma biomarkers Jie Wang 1, Qi Huang 1, Xing Chen 2, Zhiwen You 2, Kun He 1, Xiaoxie Mao 1, Yiyun Huang 3, Nicolai Franzmeier 4 5 6, Michael Schöll 6, Tengfei Guo 7, Jun Zhao 2, Yihui Guan 1, Ruiqing Ni 8, Binyin Li 9, Fang Xie 1 10 Affiliations Expand PMID: 40432308 PMCID: PMC12117192 DOI: 10.1002/alz.70333
Non-invasive arterial input function estimation using an MRA atlas and machine learning Rajat Vashistha 1 2, Hamed Moradi 1 2 3, Amanda Hammond 3, Kieran O'Brien 3, Axel Rominger 4, Hasan Sari 5 4, Kuangyu Shi 4, Viktor Vegh 6 7, David Reutens 1 2 Affiliations Expand PMID: 40408028 PMCID: PMC12102434 DOI: 10.1186/s13550-025-01253-3
Review Semin Nucl Med. 2025 May;55(3):358-370. doi: 10.1053/j.semnuclmed.2025.01.008. Epub 2025 Feb 25. AI in Breast Cancer Imaging: An Update and Future Trends Yizhou Chen 1, Xiaoliang Shao 2, Kuangyu Shi 1, Axel Rominger 1, Federico Caobelli 3 Affiliations Expand PMID: 40011118 DOI: 10.1053/j.semnuclmed.2025.01.008
Characterization of Effective Half-Life for Instant Single-Time-Point Dosimetry Using Machine Learning Carlos Vinícius Gomes 1 2 3, Yizhou Chen 1, Isabel Rauscher 4, Song Xue 1 5, Andrei Gafita 4 6, Jiaxi Hu 1, Robert Seifert 1, Lorenzo Mercolli 1, Julia Brosch-Lenz 4 7, Jimin Hong 1, Marc Ryhiner 1, Sibylle Ziegler 8 9, Ali Afshar-Oromieh 1, Axel Rominger 1, Matthias Eiber 4, Thiago Viana Miranda Lima 2 10, Kuangyu Shi 11 Affiliations Expand PMID: 40113223 PMCID: PMC12051766 DOI: 10.2967/jnumed.124.268175
Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Ethical, Regulatory, and Socioeconomic Dimensions of Theranostic Digital Twins Lidia Strigari 1, Jazmin Schwarz 2, Tyler Bradshaw 3, Julia Brosch-Lenz 4, Geoffrey Currie 5, Georges El-Fakhri 6, Abhinav K Jha 7, Signe Mežinska 8, Neeta Pandit-Taskar 9 10, Emilie Roncali 11, Kuangyu Shi 12, Carlos Uribe 13, Tahir Yusufaly 14, Habib Zaidi 15 16, Arman Rahmim 17, Babak Saboury 18 Affiliations Expand PMID: 39848769 PMCID: PMC12051771 DOI: 10.2967/jnumed.124.268186
Case Reports Clin Nucl Med. 2025 May 1;50(5):e320-e321. doi: 10.1097/RLU.0000000000005716. Epub 2025 Apr 7. Ectopic Right Kidney Imaged With Dynamic 82Rb PET/CT Nasir Gözlügöl 1, Hasan Sari, Ali Afshar-Oromieh, Axel Rominger, Federico Caobelli Affiliations Expand PMID: 40179306 DOI: 10.1097/RLU.0000000000005716
PSMA PET/CT based multimodal deep learning model for accurate prediction of pelvic lymph-node metastases in prostate cancer patients identified as candidates for extended pelvic lymph node dissection by preoperative nomograms Qiaoke Ma # 1, Bei Chen # 1, Robert Seifert 2, Rui Zhou 3, Ling Xiao 1, Jinhui Yang 1, Axel Rominger 2, Kuangyu Shi 2 4, Weikai Li 5, Yongxiang Tang 6 7 8, Shuo Hu 9 10 11 Affiliations Expand PMID: 39865180 DOI: 10.1007/s00259-024-07065-2
Review Semin Nucl Med. 2025 May;55(3):313-327. doi: 10.1053/j.semnuclmed.2025.01.006. Epub 2025 Feb 10. The Evolution of Artificial Intelligence in Nuclear Medicine Leonor Lopes 1, Alejandro Lopez-Montes 2, Yizhou Chen 3, Pia Koller 4, Narendra Rathod 2, August Blomgren 3, Federico Caobelli 2, Axel Rominger 2, Kuangyu Shi 5, Robert Seifert 2 Affiliations Expand PMID: 39934005 DOI: 10.1053/j.semnuclmed.2025.01.006
Transcriptionally downregulated GABAergic genes associated with synaptic density network dysfunction in temporal lobe epilepsy Rong Li # 1 2, Ling Xiao # 3, Honghao Han # 1 2, Hongyu Long 4, Wei Liao 1 2, Zhenzhe Yang 1 2, Haoyue Zhu 4, Xuyang Wang 1 2, Ting Zou 1 2, Yongwen Huang 1 2, Bharat B Biswal 1 2, Ming Zhou 3, Jian Li 3, Yulai Li 3, Axel Rominger 5, Kuangyu Shi 5 6, Huafu Chen 7 8, Yongxiang Tang 9 10 11, Li Feng 12 13, Shuo Hu 14 15 16 Affiliations Expand PMID: 39777496 DOI: 10.1007/s00259-024-07054-5
Using interpretable deep learning radiomics model to diagnose and predict progression of early AD disease spectrum: a preliminary [18F]FDG PET study Jiehui Jiang # 1, Chenyang Li # 2, Jiaying Lu # 3, Jie Sun 2, Xiaoming Sun 4, Jiacheng Yang 2, Luyao Wang 2, Chuantao Zuo 5 6, Kuangyu Shi 7; Alzheimer’s Disease Neuroimaging Initiative Affiliations Expand PMID: 39477837 DOI: 10.1007/s00330-024-11158-9
Clin Nucl Med. 2025 May 1;50(5):410-418. doi: 10.1097/RLU.0000000000005724. Epub 2025 Mar 10. Using mpMRI, PSMA, and GRPR PET to Assess Focal Therapy Eligibility and Plan Treatment in Biopsy-proven Low-/Intermediate-risk Prostate Cancer: A Whole-mount Pathology-based Study Yujia Li 1, Jinhui Yang 1, Ling Xiao 1, Ming Zhou 1, Xiaomei Gao 2, Axel Rominger 3, Kuangyu Shi 3 4, Robert Seifert 3, Yi Cai 5 6, Yongxiang Tang 1 3 6, Shuo Hu 1 6 7 Affiliations Expand PMID: 40179293 DOI: 10.1097/RLU.0000000000005724
Which patients with negative PSMA-PET imaging can safely avoid biopsy for prostate cancer? a novel step towards PSMA-based biopsy-free strategy Yujia Li # 1, Jinhui Yang # 1, Ling Xiao 1, Ming Zhou 1, Jian Li 1, Yi Cai 2 3, Xiaomei Gao 4, Axel Rominger 5, Kuangyu Shi 5 6, Robert Seifert 5, Qi Su 7, Yongxiang Tang 8 9 10, Shuo Hu 11 12 13 Affiliations Expand PMID: 39862259 DOI: 10.1007/s00259-025-07089-2
Partial volume effect correction impairs the diagnostic utility of [18F]-THK-5351 PET in nonfluent-agrammatic variant primary progressive aphasia Patrick J Sommer 1, Sebastian Schuster 2, Oliver Goldhardt 3, Nobuyuki Okamura 4, Felix Mueller-Sarnowski 5, Maximilian Scheifele 6, Florian Eckenweber 6, Annika Kreuzer 6, Maria Griessl 6, Peter Bartenstein 6, Thomas Wegehaupt 3, Lucas Wolski 3, Josef Priller 7, Axel Rominger 8, Leonie Beyer 6, Timo Grimmer 3, Matthias Brendel 9 Affiliations Expand PMID: 40288050 PMCID: PMC12056779 DOI: 10.1016/j.nicl.2025.103789
External phantom-based validation of a deep-learning network trained for upscaling of digital low count PET data Anja Braune 1 2 3, René Hosch 4 5, David Kersting 6, Juliane Müller 7, Frank Hofheinz 8, Ken Herrmann 6, Felix Nensa 4 5, Jörg Kotzerke # 7 9, Robert Seifert # 6 10 Affiliations Expand PMID: 40237913 PMCID: PMC12003253 DOI: 10.1186/s40658-025-00745-4
Radioactivity levels in the saliva of patients undergoing targeted radioligand therapy with [177Lu]Lu-PSMA-I&T and [177Lu]Lu-DOTA-TOC Christian Schedeit 1, Nasir Gözlügöl 2, Radi Saiyed Alsheikh 2, Mohamed Shelan 3, Robert Seifert 2, Federico Caobelli 2, Urs Borner 4, Tateyuki Iizuka 1, Benoît Schaller 1, Axel Rominger 2, Paul Cumming 2 5, Ali Afshar-Oromieh 6, Konstantinos G Zeimpekis 2 Affiliations Expand PMID: 40214824 PMCID: PMC11991938 DOI: 10.1007/s00784-025-06300-w
A deep learning method for the recovery of standard-dose imaging quality from ultra-low-dose PET on wavelet domain Song Xue 1 2, Fanxuan Liu 1, Hanzhong Wang 3 4 5 6, Hong Zhu 7, Hasan Sari 1 8, Marco Viscione 1, Raphael Sznitman 2, Axel Rominger 1, Rui Guo 9 10 11 12, Biao Li 13 14 15 16, Kuangyu Shi 1 7 2 Affiliations Expand PMID: 39585354 DOI: 10.1007/s00259-024-06994-2
Computational Nuclear Oncology Toward Precision Radiopharmaceutical Therapies: Current Tools, Techniques, and Uncharted Territories Tahir Yusufaly 1, Emilie Roncali 2, Julia Brosch-Lenz 3, Carlos Uribe 4, Abhinav K Jha 5, Geoffrey Currie 6, Joyita Dutta 7, Georges El-Fakhri 8, Helena McMeekin 9, Neeta Pandit-Taskar 10 11, Jazmin Schwartz 12, Kuangyu Shi 13, Lidia Strigari 14, Habib Zaidi 15 16, Babak Saboury 17, Arman Rahmim 4 18 Affiliations Expand PMID: 39947910 PMCID: PMC11960611 DOI: 10.2967/jnumed.124.267927
Influence of dosimetry accuracy on the correlation with treatment outcome in a preliminary PSMA radiopharmaceutical therapy study Jiaxi Hu 1, Robert Seifert 1, Sofia Karkampouna 2 3, Carlos Vinicius Gomes 1, Song Xue 1 4, Ali Afshar-Ormieh 1, Axel Rominger 1, Kuangyu Shi 5 Affiliations Expand PMID: 39704811 PMCID: PMC11928392 DOI: 10.1007/s00259-024-07010-3
Prediction of pink esthetic score using deep learning: A proof of concept Ziang Wu 1, Yizhou Chen 2, Xinbo Yu 3, Feng Wang 4, Haochen Shi 5, Fang Qu 1, Yingyi Shen 1, Xiaojun Chen 6, Chun Xu 7 Affiliations Expand PMID: 39892738 DOI: 10.1016/j.jdent.2025.105601
Eur J Nucl Med Mol Imaging. 2025 Apr;52(5):1658-1670. doi: 10.1007/s00259-024-07060-7. Epub 2025 Jan 11. Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI David Kersting # 1, Katarzyna Borys # 2 3, Alina Küper 4, Moon Kim 2 3, Johannes Haubold 2 3, Tsepo Goerttler 4, Lale Umutlu 3, Pedro Fragoso Costa 4, Jens Kleesiek 2 5 6, Christoph Rischpler 4 7, Felix Nensa 2 3, Ken Herrmann 4, Wolfgang P Fendler 4, Manuel Weber 4, René Hosch # 2 3, Robert Seifert # 4 8 Affiliations Expand PMID: 39794510 PMCID: PMC11928425 DOI: 10.1007/s00259-024-07060-7
Unveiling the biological side of PET-derived biomarkers: a simulation-based approach applied to PDAC assessment Lara Cavinato 1 2, Jimin Hong 3, Martin Wartenberg 4, Stefan Reinhard 4, Robert Seifert 3, Paolo Zunino 5, Andrea Manzoni 5, Francesca Ieva 5 6, Arturo Chiti 7 8, Axel Rominger 3, Kuangyu Shi 3 Affiliations Expand PMID: 39586846 DOI: 10.1007/s00259-024-06958-6
Prognostic value of [18F]FDG- and PSMA-PET in patients evaluated for [177Lu]Lu-PSMA therapy of mCRPC Tugce Telli # 1 2 3, Leonor Lopes # 4, Madeleine Karpinski 5 6 7, Kim M Pabst 5 6 7, Viktor Grünwald 6 7 8, Kuangyu Shi 4, Boris Hadaschik 6 7 8, Claudia Kesch 6 7 8, Lale Umutlu 6 9, Ken Herrmann 5 6 7, Robert Seifert # 5 6 7 4, Wolfgang P Fendler # 5 6 7 Affiliations Expand PMID: 40113645 PMCID: PMC12222416 DOI: 10.1007/s00259-025-07198-y
Morphinan Alkaloids and Their Transformations: A Historical Perspective of a Century of Opioid Research in Hungary János Marton 1, Paul Cumming 2 3, Kenner C Rice 4, Joannes T M Linders 5 Affiliations Expand PMID: 40141378 PMCID: PMC11943231 DOI: 10.3390/ijms26062736
Distinguishing Low Expression Levels of Human Epidermal Growth Factor Receptor 2 in Breast Cancer: Insights from Qualitative and Quantitative Magnetic Resonance Imaging Analysis Yiyuan Shen 1 2, Xu Zhang 1 2, Jinlong Zheng 1 2, Simin Wang 1 2, Jie Ding 1 2, Shiyun Sun 1 2, Qianming Bai 2 3, Caixia Fu 4, Junlong Wang 5, Jing Gong 1 2, Chao You 1 2, Yajia Gu 1 2 Affiliations Expand PMID: 40137571 PMCID: PMC11945706 DOI: 10.3390/tomography11030031
3D full-dose brain-PET volume recovery from low-dose data through deep learning: quantitative assessment and clinical evaluation Rui Guo # 1 2, Jiale Wang # 1 3, Ying Miao # 1 2, Xinyu Zhang 1 2, Song Xue 4, Yu Zhang 1 2, Kuangyu Shi 4 5, Biao Li 6 7, Guoyan Zheng 8 Affiliations Expand PMID: 39609283 DOI: 10.1007/s00330-024-11225-1
Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study Klemens Egger 1, Javier Jareño Redondo 2, Jovin Müller 2, Joëlle Dornbierer 3, John Smallridge 4, Helena D Aicher 5, Daniel Meling 6, Per Müller 2, Jonas Kost 7, Maxim Puchkov 7, Angela Äbelö 8, Erich Seifritz 3, Boris B Quednow 3, Robin von Rotz 4, Milan Scheidegger 9, Dario A Dornbierer 4 Affiliations Expand PMID: 39923404 DOI: 10.1016/j.biopha.2025.117908
ER+ HER2- Invasive Breast Cancer: Tumor Remission following Viscum Album Extract/Influenza Vaccine Treatment - A Report of 2 Cases Saphira Kaesbach 1, Alexander Hintze 1, Swantje Engelbrecht 2, Martin Wartenberg 3, Arnoud J Templeton 4 5 Affiliations Expand PMID: 39938501 PMCID: PMC11991746 DOI: 10.1159/000544082
A cutting-edge technology for the future of nuclear medicine Andor W J M Glaudemans 1, Adriaan A Lammertsma 2, Simon R Cherry 3, Paola A Erba 2 4, Axel Rominger 5, Rudi A J O Dierckx 2, Ronald Boellaard 2 6, Alexander Hammers 7 8, Rodney J Hicks 9 10, Riemer H J A Slart 2 Affiliations Expand PMID: 39661126 DOI: 10.1007/s00259-024-07028-7
Dopaminergic PET to SPECT domain adaptation: a cycle GAN translation approach Leonor Lopes 1 2, Fangyang Jiao 3, Song Xue 1 4, Thomas Pyka 1 5, Korbinian Krieger 1, Jingjie Ge 3 6, Qian Xu 3 6, Rachid Fahmi 7, Bruce Spottiswoode 7, Ahmed Soliman 7, Ralph Buchert 8, Matthias Brendel 9 10 11, Jimin Hong 1 2, Yihui Guan 3 6, Claudio L A Bassetti 12, Axel Rominger 1, Chuantao Zuo 3 6, Kuangyu Shi 13 14, Ping Wu 15 16 Affiliations Expand PMID: 39557690 PMCID: PMC11754385 DOI: 10.1007/s00259-024-06961-x
Expert consensus on workflow of PET/CT with long axial field-of-view Guobing Liu # 1 2 3, Yushen Gu # 4 1 2 3, Martina Sollini # 5 6, Alexandra Lazar 5, Florent L Besson 7 8, Sijin Li 9, Zhifang Wu 9, Lorenzo Nardo 10, Akram Al-Ibraheem 11 12, Jiefu Zheng 13, Harshad R Kulkarni 14 15, Axel Rominger 16, Wei Fan 17, Xiaohua Zhu 18, Xinming Zhao 19, Hubing Wu 20, Jianjun Liu 21, Biao Li 22, Zhaoping Cheng 23, Ruimin Wang 24, Baixuan Xu 24, Denis Agostini 25, Han Tang 3 26, Lijie Tan 3 26, Zhi Yang 27, Li Huo 28 29, Jianying Gu 30 31 32 33, Hongcheng Shi 34 35 36 37 38 39 Affiliations Expand PMID: 39520515 DOI: 10.1007/s00259-024-06968-4
Hybrid cardiovascular imaging. A clinical consensus statement of the european association of nuclear medicine (EANM) and the european association of cardiovascular imaging (EACVI) of the ESC Federico Caobelli 1, Marc R Dweck 2, Domenico Albano 3, Olivier Gheysens 4, Panagiotis Georgoulias 5, Stephan Nekolla 6, Olivier Lairez 7, Lucia Leccisotti 8, Marc Lubberink 9, Samia Massalha 10, Carmela Nappi 11, Christoph Rischpler 12, Antti Saraste 13, Fabien Hyafil 14 Affiliations Expand PMID: 39436435 PMCID: PMC11754344 DOI: 10.1007/s00259-024-06946-w
Long-axial field-of-view PET/CT improves radiomics feature reliability Ian L Alberts 1 2, Song Xue 3, Hasan Sari 3 4, Lara Cavinato 3 5, George Prenosil 3, Ali Afshar-Oromieh 3, Clemens Mingels 3, Kuangyu Shi 3, Federico Caobelli 3, Arman Rahmim 6 7, Thomas Pyka 3, Axel Rominger 3 Affiliations Expand PMID: 39477863 DOI: 10.1007/s00259-024-06921-5
Long axial field-of-view PET imaging of intraarterial 2-[18F]FDG injection Korbinian Krieger 1 2, Carola Maria Bregenzer 3, Luis Weissenrieder 3 4, Axel Rominger 3, Thomas Pyka 3 Affiliations Expand PMID: 39261333 PMCID: PMC11754309 DOI: 10.1007/s00259-024-06898-1
Using a novel PSMA-PET and PSA-based model to enhance the diagnostic accuracy for clinically significant prostate cancer and avoid unnecessary biopsy in men with PI-RADS ≤ 3 MRI Yujia Li # 1, Jian Li # 1, Jinhui Yang 1, Ling Xiao 1, Ming Zhou 1, Yi Cai 2 3, Axel Rominger 4, Kuangyu Shi 4 5, Robert Seifert 4, Xiaomei Gao 6, Yongxiang Tang 7 8 9 10, Shuo Hu 11 12 13 Affiliations Expand PMID: 39404788 DOI: 10.1007/s00259-024-06949-7
Evaluation of three diagnostic algorithms to reduce normal scan rates, radiation exposure and costs in patients with suspected chronic coronary syndrome referred for 82Rb-Positron Emission Tomography (82Rb-PET) Simon M Frey 1 2, Gabrielle Huré 2, Jan-Philipp Leibfarth 2, Kathrin Thommen 3, Melissa L Amrein 2, Ibrahim Schaefer 2, Klara Rumora 2, Igor G Schneider 3 2, Federico Caobelli 4, Damian Wild 5, Philip Haaf 3 2, Felix Mahfoud 3 2, Christian Müller 3 2, Michael J Zellweger 3 2 Affiliations Expand PMID: 39800434 PMCID: PMC11751945 DOI: 10.1136/openhrt-2024-003086
Accelerated Molecular Transportation in the Brain Extracellular Space with 755-nm Light Attenuates Post-Stroke Cognitive Impairment in Rats Liu Yang 1 2, Yajuan Gao 1 2, Leonor Serrano Lopes 3 4, Jingge Lian 1 2, Wanyi Fu 5 6, Hanbo Tan 5, Shuangfeng Yang 7, Zhaoheng Xie 5, Yixing Huang 5, Jicong Zhang 8, Yanye Lu 5, Hao Tang 9, Bo Xiong 9, Xunbin Wei 5, Lide Xie 10, Yun Peng 7, Xinyu Liu 5, Hongbin Han 1 2 5 10 Affiliations Expand PMID: 40330544 PMCID: PMC12053100 DOI: 10.34133/cbsystems.0262
Chemerin-CMKLR1 differentially mediated OGD/R-induced mitochondrial dysfunction, oxidative stress, and autophagy in microglia and neurons Pei-Yan Long 1, Zhi Tang 2, Na Cai 3, Zhi-Qin Yan 3, Xiao Gao 3, Zheng-Wei Wang 3, Zhi-Zhong Guan 2, Xiao-Lan Qi 2, Ruiqing Ni 4, Yan Xiao 5 Affiliations Expand PMID: 41151300 DOI: 10.1016/j.biopha.2025.118702
Enhancing global sensitivity and uncertainty quantification in medical image reconstruction with Monte Carlo arbitrary-masked mamba Jiahao Huang 1, Liutao Yang 2, Fanwen Wang 1, Yinzhe Wu 1, Yang Nan 3, Weiwen Wu 4, Chengyan Wang 5, Kuangyu Shi 6, Angelica I Aviles-Rivero 7, Carola-Bibiane Schönlieb 7, Daoqiang Zhang 2, Guang Yang 8 Affiliations Expand PMID: 39255733 DOI: 10.1016/j.media.2024.103334
Evaluation of long axial field-of-view (LAFOV) PET/CT for post-treatment dosimetry in Yttrium-90 radioembolization of liver tumors: a comparative study with conventional SPECT imaging Konstantinos G Zeimpekis 1, Hasan Sari 2 3, Nasir Gözlügöl 2, Ngwe Rawlings Achangwa 2, Kuangyu Shi 2, Marc Schindewolf 4, Ali Afshar-Oromieh 2, Axel Rominger 2, Robert Seifert 2 Affiliations Expand PMID: 39730786 PMCID: PMC11839895 DOI: 10.1007/s00259-024-07034-9
First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT Lorenzo Mercolli 1 2 3, William M Steinberger 4, Pascal V Grundler 5, Anzhelika Moiseeva 5, Saverio Braccini 3, Maurizio Conti 4, Paweł Moskal 6 7, Narendra Rathod 1 2, Axel Rominger 1, Hasan Sari 1 2 8, Roger Schibli 5 9, Robert Seifert 1 2, Kuangyu Shi 1 2, Ewa Ł Stepień 6 7, Nicholas P van der Meulen 5 10 Affiliations Expand PMID: 41357528 PMCID: PMC12675369 DOI: 10.3389/fnume.2025.1648621
Increased levels of GFAP and purinergic P2X7 receptor in Alzheimer's disease brain are associated with Aβ, tau pathologies and synaptic loss Cinzia A Maschio 1, Oscar Moreno 2, Junlong Wang 3, Upasana Maheshwari 4, Annika Keller 4, Uwe Konietzko 1, Daniel Razansky 5, Agneta Nordberg 6, Axel Rominger 3, Christoph Hock 1 7, Jordi Llop 2, Roger M Nitsch 1 7, Ruiqing Ni 8 9 10 Affiliations Expand PMID: 41291905 PMCID: PMC12751640 DOI: 10.1186/s13195-025-01916-2
Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease Zhi Tang 1, Ting Sha 1, Yuanshang Wang 1, Yan Xiao 1, Yuanting Ding 2, Ruiqing Ni 3, Xiaolan Qi 4 Affiliations Expand PMID: 40414556 DOI: 10.1016/j.lfs.2025.123759
Meditation, psychedelics, and brain connectivity: A randomized controlled resting-state fMRI study of N,N-dimethyltryptamine and harmine in a meditation retreat Klemens Egger 1 2 3, Daniel Meling 1 4, Firuze Polat 1, Erich Seifritz 1, Mihai Avram 5, Milan Scheidegger 1 2 Affiliations Expand PMID: 41035622 PMCID: PMC12479382 DOI: 10.1162/IMAG.a.907
Meningioma Revisited: Should Whole-Body Staging with [68Ga]Ga-DOTATOC PET/CT of High-Grade Meningiomas Become Standard Practice? Ekin Ermiş 1, Nicolas Bachmann 2, Katharina Lutz 3, Thomas Pyka 4 Affiliations Expand PMID: 39572225 DOI: 10.2967/jnumed.124.267934
Molecular brain imaging of psychedelic action Paul Cumming 1, Klemens Egger 2, Gitte M Knudsen 3 Affiliations Expand PMID: 40541310 DOI: 10.1016/bs.irn.2025.02.005
Molecular Imaging Studies of Alcohol Use Disorder Patrick Bach 1, Philippe de Timary 2, Gerhard Gründer 3, Paul Cumming 4 5 6 Affiliations Expand PMID: 36639552 DOI: 10.1007/7854_2022_414
Multi-modality artificial intelligence-based transthyretin amyloid cardiomyopathy detection in patients with severe aortic stenosis Isaac Shiri 1, Sebastian Balzer 1, Giovanni Baj 1 2, Benedikt Bernhard 1, Moritz Hundertmark 1, Adam Bakula 1, Masaaki Nakase 1, Daijiro Tomii 1, Giulia Barbati 2, Stephan Dobner 1, Waldo Valenzuela 3, Axel Rominger 4, Federico Caobelli 4, George C M Siontis 1, Jonas Lanz 1, Thomas Pilgrim 1, Stephan Windecker 1, Stefan Stortecky 1, Christoph Gräni 5 Affiliations Expand PMID: 39307861 PMCID: PMC11732884 DOI: 10.1007/s00259-024-06922-4
. Non-invasive large-scale imaging of concurrent neuronal, astrocytic, and hemodynamic activity with hybrid multiplexed fluorescence and magnetic resonance imaging (HyFMRI) Zhenyue Chen # 1, Yi Chen # 2 3, Irmak Gezginer # 2 3, Qingxiang Ding 1, Hikari A I Yoshihara 2 3, Xosé Luís Deán-Ben 2 3, Ruiqing Ni 2 3 4 5, Daniel Razansky 6 7 8 Affiliations Expand PMID: 40998778 PMCID: PMC12462443 DOI: 10.1038/s41377-025-02003-9
Optimizing theranostics chatbots with context-augmented large language models Pia Koller 1 2, Christoph Clement 3, Albert van Eijk 2, Robert Seifert 3, Jingjing Zhang 4, George Prenosil 3, Mike M Sathekge 5, Ken Herrmann 6 7, Richard Baum 8, Wolfgang A Weber 9, Axel Rominger 3, Kuangyu Shi 3 9 10 Affiliations Expand PMID: 40365297 PMCID: PMC12068303 DOI: 10.7150/thno.107757
Reduced synaptic vesicle protein 2A in extracellular vesicles and brains of Alzheimer's disease: associations with Aβ, tau, synaptic proteins and APOE ε4 Jana Nussbaumer 1, Aatmika Barve 2, Valentin Zufferey 2, Jeanne Espourteille 2, Tunahan Kirabali 1, Uwe Konietzko 1, Daniel Razansky 3, Axel Rominger 4, Agneta Nordberg 5, Luc Buée 6, Morvane Colin 6, Roger M Nitsch 1 7, Christoph Hock 1 7, Kevin Richetin 8 9, Ruiqing Ni 10 11 12 Affiliations Expand PMID: 40993829 PMCID: PMC12459057 DOI: 10.1186/s40035-025-00508-2
Role of Total Body PET/CT in Inflammatory Disorders Shervin Zoghi 1, Clemens Mingels 2, Ramsey D Badawi 3, Benjamin A Spencer 3, Tracy L Yarbrough 3, Lorenzo Nardo 3, Abhijit J Chaudhari 3 Affiliations Expand PMID: 39578110 PMCID: PMC11645246 DOI: 10.1053/j.semnuclmed.2024.11.001
Role of Total Body PET/CT in Inflammatory Disorders
Shervin Zoghi 1, Clemens Mingels 2, Ramsey D Badawi 3, Benjamin A Spencer 3, Tracy L Yarbrough 3, Lorenzo Nardo 3, Abhijit J Chaudhari 3 Affiliations Expand PMID: 39578110 PMCID: PMC11645246 DOI: 10.1053/j.semnuclmed.2024.11.001
Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson's disease Benjamin F Combes # 1, Sandeep Kumar Kalva # 2 3, Pierre-Louis Benveniste 4 5, Agathe Tournant 2, Man Hoi Law 1, Joshua Newton 4, Maik Krüger 1, Rebecca Z Weber 1, Inês Dias 6, Daniela Noain 6 7 8, Xose Luis Dean-Ben 2 3, Uwe Konietzko 1, Christian R Baumann 6 7 8, Per-Göran Gillberg 9, Christoph Hock 1 10, Roger M Nitsch 1 10, Julien Cohen-Adad 4 5, Daniel Razansky 11 12, Ruiqing Ni 13 14 15 Affiliations Expand PMID: 39382580 PMCID: PMC11732882 DOI: 10.1007/s00259-024-06938-w
Total-Body PET/CT: Challenges and Opportunities Clemens Mingels 1, Kevin J Chung 2, Austin R Pantel 3, Axel Rominger 4, Ian Alberts 5, Benjamin A Spencer 2, Lorenzo Nardo 2, Thomas Pyka 6 Affiliations Expand PMID: 39341688 DOI: 10.1053/j.semnuclmed.2024.08.003 Free article
Total Body PET/CT: Clinical Value and Future Aspects of Quantification in Static and Dynamic Imaging Narendra Rathod 1, Warissara Jutidamrongphan 2, Wolfram Andreas Bosbach 2, Yizhou Chen 2, Jan Luca Penner 2, Hasan Sari 2, Konstantinos Zeimpekis 2, Alejandro López Montes 2, Pawel Moskal 3, Ewa Stepien 3, Kuangyu Shi 2, Axel Rominger 2, Robert Seifert 2 Affiliations Expand PMID: 39616013 DOI: 10.1053/j.semnuclmed.2024.11.004
Total Body PET/CT: Future Aspects Felipe Godinez 1, Clemens Mingels 2, Reimund Bayerlein 3, Brahim Mehadji 4, Lorenzo Nardo 4 Affiliations Expand PMID: 39542814 PMCID: PMC11977673 DOI: 10.1053/j.semnuclmed.2024.10.011
Transcriptomic Profiling of the Tumor Immune Microenvironment Reveals Prognostic Markers in mCRPC Patients Treated with LuPSMA Therapy Analena Handke 1 2, Leonor Lopes 3, Claudia Kesch 1, Christopher Darr 1, Elai Davicioni 4, Kuangyu Shi 3, Tugce Telli 5, Wolfgang P Fendler 5, Ken Herrmann 5, Katharina Lückerath 5, Boris Hadaschik 1, Robert Seifert 5 3 Affiliations Expand PMID: 41041047 PMCID: PMC12486015 DOI: 10.7150/thno.113614
Visual reading for [18F]Florzolotau Tau PET scans in progressive supranuclear palsy Feng-Tao Liu 1, Jia-Ying Lu 2, Xin-Yi Li 1, Jing-Jie Ge 2, Yi-Min Sun 1, Tzu-Chen Yen 3, Fang-Yang Jiao 2, Ming-Jia Chen 1, Jun Zhao 4, Rui-Xin Yao 1, Gan Tang 1, Hao Xu 5, Xiao-Li Lan 6, Jie Lu 7, Rui-Xue Cui 8, Matthias Brendel 9 10 11, Kuangyu Shi 12 13, Yi-Hui Guan 2, Axel Rominger 12, Jian Wang 14, Chuan-Tao Zuo 15 16 17; Progressive Supranuclear Palsy Neuroimage Initiative (PSPNI) Affiliations Expand PMID: 39352424 DOI: 10.1007/s00259-024-06923-3
What Role Does PET/MRI Play in Musculoskeletal Disorders? Tugce Telli 1, Mélanie Desaulniers 2, Thomas Pyka 3, Federico Caobelli 3, Sophia Forstmann 4, Lale Umutlu 5, Wolfgang P Fendler 6, Axel Rominger 3, Ken Herrmann 6, Robert Seifert 7 Affiliations Expand PMID: 38044175 DOI: 10.1053/j.semnuclmed.2023.11.004